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theperksofbeing-kate:

daily reminder that the boy you’re in love with at 16 probably won’t matter when you’re 25.

daily reminder that the math test you failed your freshman year of high school probably won’t matter when you’re graduating college.

daily reminder that the problems you’re facing today may seem like the worlds end, but they will not matter in a year.

daily reminder that you’re going to be okay.

everything is going to be okay.

My cousin Helen, who is in her 90s now, was in the Warsaw ghetto during World War II. She and a bunch of the girls in the ghetto had to do sewing each day. And if you were found with a book, it was an automatic death penalty. She had gotten hold of a copy of ‘Gone With the Wind’, and she would take three or four hours out of her sleeping time each night to read. And then, during the hour or so when they were sewing the next day, she would tell them all the story. These girls were risking certain death for a story. And when she told me that story herself, it actually made what I do feel more important. Because giving people stories is not a luxury. It’s actually one of the things that you live and die for.
 Neil Gaiman (via jaynestown)

(Source: lupanthropy)

neurosciencestuff:

(Figure 1: Fluorescent labeling reveals mossy fibers (red) projecting from the dentate gyrus (green) into the CA2 subregion (orange). Credit: Keigo Kohara, RIKEN–MIT Center for Neural Circuit Genetics)

Novel combination of techniques reveals new details about the neuronal networks for memory

Learning and memory are believed to occur as a result of the strengthening of synaptic connections among neurons in a brain structure called the hippocampus. The hippocampus consists of five subregions, and a circuit formed between four of these is thought to be particularly important for memory formation. Keigo Kohara and colleagues from the RIKEN–MIT Center for Neural Circuit Genetics and RIKEN BioResource Center have now identified a previously unknown circuit involving the fifth subregion.

For a hundred years, memory research has typically focused on the main circuit, which projects from layer II of the entorhinal cortex via the dentate gyrus to subregion CA3 and then CA1. Subregion CA2 lies between CA3 and CA1 but its cells are less elaborate than those of its neighbors and were thought not to receive inputs from the dentate gyrus.

Kohara and his colleagues combined anatomical, genetic and physiological techniques to analyze the connections formed by neurons in the CA2 subregion of the hippocampus in unprecedented detail. First, they identified the CA2 subregion by examining the expression of three genes that encode proteins called RGS14, PCP4 and STEP using a fluorescent marker to label nerve fibers—a technique called fluorescent immunohistochemistry. They were surprised to discover that, contrary to expectations, CA2 neurons receive extensive inputs from cells in the dentate gyrus (Fig.1).

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fucktonofanatomyreferences:

helpyoudraw:

Sitting Poses References

Kneeling and Sitting Stock Pack by KxharaSitting

Stock Pack 2 by KxharaSitting

Stock Pack 3 by KxharaSailor

Sitting 27 by SenshiStock

Tuxedo Jay Sitting 2 by SenshiStock

Sailor Team Sitting 3 by SenshiStock

Tuxedo Jay Sitting 3 by SenshiStock

Pose ref: sitting leaning forward turn around by Sinned-angel-stock

Pose ref: sitting cross legged turn around by Sinned-angel-stock

Pose ref: sitting turnaround by Sinned-angel-stock


A superb fuck-ton of human pose references.

(Source: old-helpyoudraw)

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